Pirates, not geniuses. https://www.imdb.com/title/tt0168122/

Rapid aging happens like growth spurts. Around 40-44 apparently again around 65. Small print becomes a problem, body does not handle alcohol as before, body aches and pains become constant. Exercise is essential, but a setback from an injury or sedentary lifestyle is difficult to escape from.

And failing to burn the right ones.