This and then the new about regrowing teeth. Its a very exciting time in medicine.
If you think anyone but the elite will be able to afford or procure these procedures, you’re incredibly optimistic.
As soon as it gets approved, some shitty corporation will purchase the patent and lock it behind a paywall for 80+ year old geriatrics with zero fucks given towards people who actually deserve or need it.
So… anywhere but the USA it will be affordable(ie free) anyways? Okay.
Lol Yankee problems
I’m not a Yankee, but thanks for assuming
You’re an American, that’s what Yankee means to everybody outside the states.
Are you seriously also down here saying racist shit to a Native American so that you can roleplay some flex on what you thought was just some poor USAmerican who couldn’t afford healthcare? Your good guy scenario was dunking on a poor person in an authoritarian state?
Europeans are seriously the most bloodthirsty fucks I’ll see online, and they’re predictably the most smug about it too.
I have no idea what you’re trying to say. Are you saying he’s NOT an American because he’s indigenous? And wtf is racist? At least now I know what his comment means. You people think everybody knows the same things you do.
(I’m Asian BTW, but yeah go on)
Oh but how dare you be Asian when you were already assigned European at post /s
“It isn’t racist to call a Native American a ‘yank’ because I’m ignorant about racism.” You’re telling me that you moderate a Norwegian community, talk a shit ton about Euro nations, but you think it doesn’t make you look like a racist asshole to not know what is racist about trying to dunk on an indigenous person (who, again, you thought was just some other poor person) by calling them a term that identifies them with the occupying settler state that has committed genocide against their people.
Yeah dude, totally not a bloodthirsty chud.
This drug can be delivered via pill. It has a range of effects in reversing age related damage.
I’m not sure if it will be kept to the rich, or given out widely to justify the removal of social security, or at least jacking up the retirement age.
If the worker-slaves live longer, you don’t have to indoctrinate & capture new ones quite as often!
I’d like my partners knees to work again so they can do the things they like as they age, like riding bikes or hiking.
Finally some good fucking news.
This is just epic news. Well done all the scientists for making this happen. :)
I’m glad to hear that stuff like this is still going on. Nice!
in fact, we’re in the early days of human gene technology, hormone therapy, biochemistry tempering etc.
Wow, this is really exciting. I guess it’ll take years more research before we’ll know if this can benefit humans, but if they can replicate the results with humans then it could potentially prevent chronic pain and mobility issues in millions of people.
Hopefully not just humans. Many dogs for example suffer from the very same issues when they get older.
Good. Biological aging is nothing more than a series of processes, not an inherent property of atoms, and it’s time we start getting serious about anti-aging and life extension.
But probably not, seeing what the world is like.
People have been seeking life extension for all of recorded history.
How about not life extension but quality of life extension instead (e.g. this post)
Indeed, I don’t really feel like living for more more than 90 years, I just want to be able to do what I like to do until I die.
I didn’t realize people weren’t being serious about it this whole time. The tens of millions of dollars of research grants seemed pretty serious.
Only the rich will benefit.
… for the first 20 years
… and everybody else outside the US
Its mostly billionaires who will be able to benefit from life extension… do you really want a world where trump, musk, and all their silicon valley friends rule the world until they turn 300 years old?
Luckily there’s no vaccine against guillotines.
No worries about that, there is no changing the maximum age seemingly, not unless you genetically engineered babies with tech we don’t have yet.
Everyone is born with stem cells that carry so many copies of cells that are preprogrammed to die after a point to then be replaced by those stem cells. No drug can make more copies after the fact.
Then of course the dna gets denatured just by radiation and pollution and time.
Neither of these will or can be solved after someone is born. They can extend the average lifespan of a group, but they can’t exceed the maximum, which has remained constant throughout human history even as the average has changed drastically.
I thought the central problem was telemore degeneration, not anything to do with stem cells per se.
Happy to be corrected if wrong; I never worked anywhere near this category in my very long ago now pharma/biotech phase.
That is part of it, which is what I alluded to in the degeneration of the dna. The stem cell thing too though. Our bodies aren’t programmed to live beyond a certain point. We learned about this in a Nature of Disease course at University.
What’s the maximum? About 120?
Imagine having 100 or more healthy years. That seems like sci-fi, but may be possible one day still.
It will also mean working until you’re 100 before the national pension kicks in unfortunately lol
National pension
Ngl, you had me in the first half…
They nearly had me in the first quarter, but now I no longer believe I’ll ever see it. Not enough young people are born. My generation is enough to support the current old people, but there won’t be enough people to support my generation.
Are there enough people at the current system where the top 1% get 99% of the resources? ¯\_(ツ)_/¯
But there will 100% be enough people to keep the basics going
We are thousands of times more efficient than we were a couple hundred years ago.
The top 1% don’t get 99% of the resources, they get 99% of imaginary wealth. It can’t be sold off en masse.
Ergo, we don’t have a magical extra 100x increase in actual goods and other physical resources per person coming if we just kill the 1%. Things could be distributed much more fairly for sure, but it’s not as simple as “these few people own everything so if they’re gone, everyone else is a millionaire”.
Anyway, much of the “basics” is going to be in person care work with an aging society. We haven’t handed that off to AI yet, nor medicine, but once that’s happened then yes we can actually handle social safety nets in an aging society. Right now the solution they’re going for is a constant increase in retirement age to keep the tax revenue high enough to pay for retired people’s needs.
Ready for someone to tell me why this unfortunately won’t work / become mainstream
Well, this same drug (working name MF-300) is a PDGH-15 inhibitor and has already been through phase 1 human trials for a separate condition.
Because PDGH-15 also causes age related muscle weakness.
Now, PDGH-15 also plays a role in cancer prevention, and there may be a few other less obvious functions.
I don’t know if the results of the phase 1 trials have been published yet, but it’s been a while since I checked.
I’ve been hearing about MF-300 for a little under a year, and with these same claims about restoring cartilage.
Money, usually. Or cancer. God i sound depressing 😄
Money cancer.
Ah, the billionaires again.
I want this so bad, I have lost all cartilage in my wrists and I don’t want to get them fused.
I couldn’t imagine how shitty that must be, I really hope this advancement does help you regrow yours so you don’t have to get them fused.
I would like to order one new left knee cartilage please!
Americans, we get it, you have no healthcare system worth the name. Stop assuming nobody else worldwide can get the meds either.
Sorry, is this not meant to sound like you’re a Eurocentrist douchebag? Medical care and resources are already not distributed proportionately throughout the world exactly because a small number of nations benefit from a brutally extractive colonial system that requires the dehumanization of other groups to exist.
The US doesn’t have a fucking healthcare system because it is a settler-colonial, imperialist military power that holds up the capitalist system that Europeans are such proud benefactors of. They violently enforce a system that inflicts as much precarity and vulnerability as possible on its people because it depends on preventing as many unprivileged people as possible from gaining enough resources to muster an effective challenge to its power within the metropole while maintaining its legitimacy to its more privileged working classes.
So, what the fuck are you bitching about? Americans saying that people won’t be able to afford it? They’re correct, most people will not have access to it so that fucks like you can thanks to the US guarding the loot. Fuck’s sake with you people.
Edit: Before any Euros try to bitch and whine about how unfair it is that you’re still colonizers, I do not care. I don’t fucking care. We are not going to do this thing where you can bitch about the US and pretend like you aren’t world destroyers for the same exact fucking reason it is. If you are not critical of how many EU and European settler nations have the wealth to sustain a healthcare system and quality of life that makes access to medicine an entitlement instead of a privilege, you’re not a serious person.
I’m Asian. My country was colonised by Europeans till half a century ago.
Keep going, this is funny. We’ve gone from ‘America is the only nation on earth’ to ‘oh yeah, Europe exists too’.
Maybe orioler25 will figure out that there’s more to the world than only the US and EU :D
I’m Eastern European, my country was exploited by USSR until less than 40 years ago. My bad for getting excited about the prospect of being able to walk in old age, it’s all my fault for -checks notes- joining a freedom of trade and movement organisation
my country was exploited by USSR
Do you have a source for that? The inefficiencies of Communism and the lack of cheap third world resources is not the same as being colonised or post-colonised like a third world country.
Not necessarily what you’re looking for, but provides some interesting context for others
Why not? It shows that the USSR was doing the opposite.
However, especially by the end, the USSR was effectively paying to keep satellites afloat.
The first comment mentions as exploitation the dismantled production lines from East Germany. Counting war reparations as exploitation is not a honest argument.
The author shifts the tone latet-on.
Or maybe you could show a little sympathy once in a while
America did this shit to itself
And the civilised world gets dragged into the bullshit
And before you whine, the majority of Americans are a part of the problem in one way or another
Your society (for want of a better term) has gotten what it collectively wants
You try running into comments thinking they’re the only nation on earth in every health article and see how long you stay sympathetic.
i have femoral head necrosis, though so technically not arthritis but that is absolutely great news for everything else
Just in time for me to get old!
This would be amazing for my wife. I mean I guess it would have been amazing if she still had her original knee. Maybe it’ll be amazing for the other knee one day.
She’s still got hips and shoulders too I hope.
They can rebuild her. They have the technology
I remember when I was a senior in high school back in the late 90s, my biology teacher mused one day that ours might be the first generation to not die of old age. I don’t know if I’m anywhere near as optimistic now as he was then, but it is incredibly exciting to think about. There have been a slew of discoveries over the past 20 years that have been building towards this, and it’s all been very fascinating. No idea if this is the grail or not, but it certainly seems like an important piece of the puzzle.
What exactly is exciting about making genocidal maniacs practically immortal?
There’ll always be genocidal maniacs. Holding back the human race because of them is idiocy.
my biology teacher mused one day that ours might be the first generation to not die of old age.
Good for you that it was not the history teacher.
I’m in this thumbnail and I want that right now.
